| Intrahepatic Cholestasis Following Abuse of Powdered Kratom (Mitragyna speciosa). | |
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MedLine Citation:
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PMID: 21528385 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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INTRODUCTION: Kratom (Mitragyna speciosa) is a common medical plant in Thailand and is known to contain mitragynine as the main alkaloid. According to an increase in published reports and calls at German poison control centers, it has been used more frequently as a drug of abuse in the western hemisphere during the last couple of years. Despite this increase, reports of severe toxicity are rare within the literature. CASE REPORT: We describe a case of a young man who presented with jaundice and pruritus after intake of kratom for 2 weeks in the absence of any other causative agent. Alkaloids of M. speciosa were detected in the urine. CONCLUSION: While M. speciosa is gaining in popularity among illicit drug users, its adverse effects remain poorly understood. This is the first published case of intrahepatic cholestasis after kratom abuse. |
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Authors:
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Friedrich G Kapp; Hans H Maurer; Volker Auwärter; Martin Winkelmann; Maren Hermanns-Clausen |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-4-29 |
Journal Detail:
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Title: Journal of medical toxicology : official journal of the American College of Medical Toxicology Volume: - ISSN: 1937-6995 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-4-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101284598 Medline TA: J Med Toxicol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Poisons Information Center VIZ-Freiburg, Department of Pediatrics and Adolescent Medicine, University Medical Center Freiburg, Mathildenstrasse 1, 79106, Freiburg, Germany, friedrich.kapp@uniklinik-freiburg.de. |
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