Document Detail


Intragraft pressures predict outcomes in hemodialysis patients with graft outflow lesions undergoing percutaneous transluminal angioplasty.
MedLine Citation:
PMID:  20665863     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
OBJECTIVES: This study is to introduce intragraft pressure (IGP) as intraprocedural parameter for outcome survey in hemodialysis patients with graft outflow lesions undergoing percutaneous transluminal angioplasty (PTA). BACKGROUND: The role of IGP on procedural endpoint and patency is unknown. METHODS: Seventy-five participants with graft outflow lesions receiving PTA were enrolled. Procedural data regarding IGP and angiographic findings were collected and the 1-year graft patency through collaboration with hemodialysis units. Analyses and comparisons among IGP, angiographic findings, and patency were conducted. Using the receiver operating characteristic (ROC) curve and Kaplan-Meier survival analysis, we intended to detect significance and the cut-off points of IGP for patency prediction, and difference in patency between the two groups divided by using the cut-off points. RESULTS: Pre-PTA and post-PTA IGP were significantly associated with 1-year patency (both significance <0.01) with 0.756 and 0.791 areas under the ROC curves, respectively. The cut-off points of pre-PTA and post-PTA IGP were closer to 106 and 47 mm Hg for prediction of 1-year patency (sensitivity = 0.76, specificity = 0.69; sensitivity = 0.79, specificity = 0.69, respectively; 95% CI). Significant reductions in 1-year patency were shown in the subjects with greater than the cut-off values, either pre-PTA or post-PTA IGP, compared with those with smaller than these values (both log rank test < 0.001). CONCLUSION: IGP might be useful to evaluate procedural endpoints and predict patency outcomes in hemodialysis patients with graft outflow lesions undergoing PTA. Patients with the greater pre-PTA or post-PTA IGP, to some level, seem to have the shorter patency.
Authors:
Chi-Cheng Lai; Hsiao-Min Chung; Han-Lin Tsai; Guang-Yuan Mar; Ching-Jiunn Tseng; Chun-Peng Liu
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions     Volume:  76     ISSN:  1522-726X     ISO Abbreviation:  Catheter Cardiovasc Interv     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100884139     Medline TA:  Catheter Cardiovasc Interv     Country:  United States    
Other Details:
Languages:  eng     Pagination:  206-11     Citation Subset:  IM    
Copyright Information:
(c) 2010 Wiley-Liss, Inc.
Affiliation:
Cardiovascular Center, Kaohsiung Veterans General Hospital, #386 Ta-Chung 1st Road, Taiwan, Republic of China.
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Comment In:
Catheter Cardiovasc Interv. 2010 Aug 1;76(2):212-3   [PMID:  20665864 ]

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