Document Detail


Intrafamilial transmission of hepatitis C virus.
MedLine Citation:
PMID:  23417615     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
HCV infection is a major public health problem worldwide. Several studies reported that HCV infection might cluster in families or households. Horizontal intrafamilial transmission of the virus has been demonstrated previously. Whether horizontal transmission makes any significant contribution to the global burden of HCV infection is still controversial and data about epidemiology and routes of transmission are uncertain. The certain diagnosis of horizontal intrafamilial transmission of HCV is based on the simultaneous presence of specific laboratory criteria, the temporal association between intrafamilial exposure and infection and the exclusion of all the potential extrafamilial routes of transmission of the infection. This review summarizes the current knowledge of epidemiology, risk factors and molecular biology of horizontal intrafamilial transmission of HCV infection. J. Med. Virol. 85:608-614, 2013. © 2013 Wiley Periodicals, Inc.
Authors:
Giuseppe Indolfi; Alessandro Nesi; Massimo Resti
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of medical virology     Volume:  85     ISSN:  1096-9071     ISO Abbreviation:  J. Med. Virol.     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-02-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7705876     Medline TA:  J Med Virol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  608-14     Citation Subset:  IM    
Copyright Information:
Copyright © 2013 Wiley Periodicals, Inc.
Affiliation:
Pediatric and Liver Unit, Meyer Children's University-Hospital of Florence, Viale Pieraccini, Firenze, Italy. g.indolfi@meyer.it.
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