Document Detail

Intraductal papillary mucinous tumour of the pancreas: differentiation of malignancy and benignancy by CT.
MedLine Citation:
PMID:  16905386     Owner:  NLM     Status:  MEDLINE    
AIM: To retrospectively identify signs predictive of malignant intraductal papillary mucinous tumour (IPMT) of the pancreas on computed tomography (CT) images. MATERIALS AND METHODS: Thirty-four benign and 21 malignant pancreatic IPMTs were evaluated. Preoperative helical CT images in these 55 cases of pathologically proven pancreatic IPMT were reviewed by two radiologists unaware of the histological grading. Tumour morphological types, locations, numbers and sizes of cystic lesions, maximum main pancreatic duct diameters, the presence of septa, mural nodule, wall thickening, and calcification in cysts, communication with the main pancreatic duct, peripancreatic haziness, protrusion of duodenal papilla, pancreatic atrophy, lymphadenopathy and distant metastasis were analysed using univariate and multivariate analysis. RESULTS: Main duct IPMTs were more likely to be malignant (71%) than branch duct (23%) or combined type IPMTs (28%; p=0.002). Among the branch duct type and combined types, large cystic lesion (p=0.018), the presence of a mural nodule (p=0.018), a thickened wall (p=0.009), and peripancreatic haziness (p=0.039) were found to predict malignancy. CONCLUSION: CT is helpful in the preoperative differentiation of malignant and benign pancreatic IPMT. The presence of a dilated main pancreatic duct, mural nodules, thickened wall and peripancreatic haziness may be used as independent predictive signs of malignancy.
S S-h Chiu; J H Lim; W J Lee; K T Chang; D K Oh; K T Lee; J K Lee; S H Choi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical radiology     Volume:  61     ISSN:  0009-9260     ISO Abbreviation:  Clin Radiol     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-08-14     Completed Date:  2006-11-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1306016     Medline TA:  Clin Radiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  776-83     Citation Subset:  IM    
Department of Radiology and Center for Imaging Science, Sungkyunkwan University School of Medicine, Seoul, Korea.
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MeSH Terms
Carcinoma, Pancreatic Ductal / radiography*
Carcinoma, Papillary / radiography*
Diagnosis, Differential
Middle Aged
Pancreatic Neoplasms / radiography*
Radiographic Image Interpretation, Computer-Assisted / methods
Retrospective Studies
Tomography, X-Ray Computed / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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