Document Detail

Intracytoplasmic type A particles in viper spleen cells.
MedLine Citation:
PMID:  190419     Owner:  NLM     Status:  MEDLINE    
Structures resembling typical type A particles were observed in paranuclear inclusions in cultured C-type particle-producing viper cells (VSW cell line). The incidence of type A particle inclusions was low (approximately 0.5% of cell profiles examined) in untreated cells, but both the incidence and size of the inclusions were slightly increased in cells treated with ethidium bromide. This is apparently the first observation of type A particles in cells of a poikilothermic vertebrate.
P D Lunger; H F Clark
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of the National Cancer Institute     Volume:  58     ISSN:  0027-8874     ISO Abbreviation:  J. Natl. Cancer Inst.     Publication Date:  1977 Mar 
Date Detail:
Created Date:  1977-04-28     Completed Date:  1977-04-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7503089     Medline TA:  J Natl Cancer Inst     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  809-11     Citation Subset:  IM    
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MeSH Terms
Cells, Cultured
Chloramphenicol / pharmacology
Ethidium / pharmacology
Inclusion Bodies, Viral* / drug effects
Retroviridae / ultrastructure
Snakes / microbiology*
Spleen / microbiology*,  ultrastructure
Virus Replication / drug effects
Reg. No./Substance:
3546-21-2/Ethidium; 56-75-7/Chloramphenicol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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