Document Detail


Intracytoplasmic sperm injection with motile and immotile frozen-thawed testicular spermatozoa (the Hungarian experience).
MedLine Citation:
PMID:  15644059     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The authors summarize their experience in 75 in vitro fertilization cycles, where frozen-thawed testicular spermatozoa were used for intracytoplasmic sperm injection. In 32 cases, motile spermatozoa could be observed in the frozen-thawed sample. In 34 cases, motility could be induced by pentoxifylline and in nine cases immotile spermatozoa, selected with hypoosmotic swelling test, were used for fertilization. The fertilization rates obtained with motile and immotile spermatozoa (66.1% versus 52.3%) were not significantly different. Our data demonstrate that freezing of testicular spermatozoa opened new possibilities for the treatment of azoospermic men. The clinical pregnancy rate per embryo transfer (ET) (21.87%) was comparable with previous results use of fresh testicular spermatozoa (27.7%). The quality and number of transferred embryos had the most significant impact on the pregnancy rate. The fertilization rate and frequency distribution of good-quality embryos were lower in the case of immotile spermatozoa, and pregnancies were only achieved when motile spermatozoa had been used.
Authors:
Sz Mátyás; Gy Papp; P Kovács; I Balogh; K Rajczy; Zs Kopa; A Bernard; T Kováts; F Krizsa; G Szmatona; I Gáti; S G Kaali
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Andrologia     Volume:  37     ISSN:  0303-4569     ISO Abbreviation:  Andrologia     Publication Date:  2005 Feb 
Date Detail:
Created Date:  2005-01-12     Completed Date:  2005-05-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0423506     Medline TA:  Andrologia     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  25-8     Citation Subset:  IM    
Affiliation:
Kaali Institute, Budapest, Hungary. kaali@axelero.hu
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MeSH Terms
Descriptor/Qualifier:
Adult
Cryopreservation
Female
Fertilization
Freezing
Humans
Male
Pregnancy
Sperm Injections, Intracytoplasmic*
Sperm Motility*

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