Document Detail


Intracytoplasmic sperm injection using surgically retrieved epididymal and testicular spermatozoa in cases of obstructive and non-obstructive azoospermia.
MedLine Citation:
PMID:  9202989     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This was a retrospective study of 115 patients who underwent 124 cycles of ICSI using surgically retrieved spermatozoa. The objective was to compare the results of ICSI in patients with obstructive azoospermia using epididymal spermatozoa (36 cycles) or testicular spermatozoa (58 cycles) with ICSI in patients with non-obstructive azoospermia using testicular spermatozoa (30 cycles). When epididymal spermatozoa were used for ICSI, the fertilization rate per injected metaphase-II oocyte and the clinical pregnancy rate per ICSI cycle were 60.4 and 25%, respectively. When testicular spermatozoa were used in obstructive cases, the fertilization rate and pregnancy rate were 57.9 and 34.5%. In non-obstructive cases the fertilization and pregnancy rates were 41.2 and 16.6%. When patients with obstructive azoospermia were regrouped according to the cause of obstruction, the fertilization and pregnancy rates were 59.1 and 35.1% in acquired obstruction and 58.7 and 24.3% in congenital obstruction. The fertilization and pregnancy rates were not statistically different (p > 0.05) when testicular or epididymal spermatozoa were used in obstructive cases; neither was statistically different (p > 0.05) when compared in patients with congenital and acquired obstruction. On the other hand, the fertilization and pregnancy rates in cases with non-obstructive azoospermia were significantly lower (p < 0.05) than in obstructive cases.
Authors:
I Fahmy; R Mansour; M Aboulghar; G Serour; A Kamal; N A Tawab; A M Ramzy; Y Amin
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  International journal of andrology     Volume:  20     ISSN:  0105-6263     ISO Abbreviation:  Int. J. Androl.     Publication Date:  1997 Feb 
Date Detail:
Created Date:  1997-07-29     Completed Date:  1997-07-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8000141     Medline TA:  Int J Androl     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  37-44     Citation Subset:  IM    
Affiliation:
Egyptian IVF-ET Center, Cairo, Egypt.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Epididymis / cytology*
Female
Fertilization in Vitro*
Humans
Male
Middle Aged
Oligospermia / therapy*
Pregnancy
Retrospective Studies
Spermatozoa*
Testis / cytology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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