Document Detail

Intracystic pressure in patients with temporal arachnoid cysts: a prospective study of preoperative complaints and postoperative outcome.
MedLine Citation:
PMID:  17158556     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Arachnoid cysts (AC) can cause a wide spectrum of clinical symptoms. Only a limited number of studies have investigated intracranial pressure in patients with AC. We wished to investigate the relationship between intracystic pressure, preoperative complaints and postoperative symptom relief in adult patients operated on for a unilateral temporal AC. MATERIAL AND METHODS: This was a prospective, population based study involving 38 adult (>18 years) patients (mean age 43 years; range 18-69) with a previously untreated unilateral temporal AC. RESULTS: For all cyst types, mean pressure was 131 mm H2O. The main preoperative complaints were headache and dizziness/nausea. By median split, patients were divided into a low pressure (<130 mm H2O) and a high pressure (>130 mm H2O) group. Patients with high intracystic pressure had a significantly higher preoperative visual analogue scale (VAS) score (54.7) than that found in patients with low intracystic pressure (39.4). Both pressure groups had a significant fall in VAS score after surgical decompression of the cyst. Intracystic pressure correlated significantly with arterial pCO2 and mean arterial pressure. CONCLUSION: There was a significant correlation between intracystic pressure and the preoperative level of complaints. Mean intracystic pressure in adult patients with unilateral temporal AC seems to lie within the limits of normal intracranial pressure. We therefore hypothesise that factors other than absolute pressure, such as altered compliance and impedance of the brain, may be involved in the pathophysiology of intracranial AC.
Christian A Helland; Knut Wester
Related Documents :
17089106 - Redefining the ace-inhibitor dose-response relationship: substantial blood pressure low...
12675866 - Dual blockade of the renin-angiotensin system versus maximal recommended dose of ace in...
8305666 - Angiotensin-converting enzyme inhibitors in cardiovascular anesthesia.
17541236 - Thrombotic microangiopathy due to malignant hypertension following corticosteroid thera...
14987346 - Inhaled nitric oxide results in deteriorating hemodynamics when administered during car...
15296896 - Repair of the descending thoracic aorta: impact of open distal anastomosis technique on...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-12-08
Journal Detail:
Title:  Journal of neurology, neurosurgery, and psychiatry     Volume:  78     ISSN:  1468-330X     ISO Abbreviation:  J. Neurol. Neurosurg. Psychiatr.     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-05-17     Completed Date:  2007-05-24     Revised Date:  2010-09-15    
Medline Journal Info:
Nlm Unique ID:  2985191R     Medline TA:  J Neurol Neurosurg Psychiatry     Country:  England    
Other Details:
Languages:  eng     Pagination:  620-3     Citation Subset:  IM    
Department of Surgical Sciences, Section for Neurosurgery, University of Bergen, Norway.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Arachnoid Cysts / complications,  physiopathology*,  surgery*
Decompression, Surgical
Dizziness / etiology
Headache / etiology
Middle Aged
Nausea / etiology
Prospective Studies
Temporal Lobe
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Targeted therapy for metastatic renal cell carcinoma.
Next Document:  Antibody responses to peptides of peripheral nerve myelin proteins P0 and P2 in patients with inflam...