Document Detail

Intracranial pressure monitoring for traumatic brain injury in the modern era.
MedLine Citation:
PMID:  19937249     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: Intracranial pressure (ICP) has become a cornerstone of care in adult and pediatric patients with traumatic brain injury (TBI).
DISCUSSION: Despite the fact that continuous monitoring of ICP in TBI was described almost 60 years ago, there are no randomized trials confirming the benefit of ICP monitoring and treatment in TBI. There is, however, a large body of clinical evidence showing that ICP monitoring influences treatment and leads to better outcomes if part of protocol-driven therapy. However, treatment of ICP has adverse effects, and there are several questions about ICP management that have yet to be definitively answered, particularly in pediatric TBI. This review examines the history and evolution of ICP monitoring, pathophysiological concepts that influence ICP interpretation, ongoing controversies, and the place of ICP monitoring in modern neurocritical care.
Llewellyn C Padayachy; Anthony A Figaji; M R Bullock
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery     Volume:  26     ISSN:  1433-0350     ISO Abbreviation:  Childs Nerv Syst     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-22     Completed Date:  2010-06-17     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  8503227     Medline TA:  Childs Nerv Syst     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  441-52     Citation Subset:  IM    
Division of Neurosurgery, School of Child and Adolescent Health, Red Cross Children's Hospital, University of Cape Town, Cape Town, South Africa.
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MeSH Terms
Brain / pathology,  physiopathology
Brain Injuries / pathology,  physiopathology*,  therapy
Intracranial Pressure / physiology*
Monitoring, Physiologic / adverse effects,  instrumentation,  methods*

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