Document Detail


Intracranial pressure increase and changes in microcirculation of the pial and iridial vessels in correlation to EEG, ECG, and arterial blood pressure.
MedLine Citation:
PMID:  1116008     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Controlled intracranial pressure increase was produced in 120 female albino rats by infusing homologous blood and saline solution into the cisterna magna. The behaviour of the brain current, cardiovascular system, and microcirculation of the iridial and pial vessels immediately after pressure increase was examined simultaneously. A direct correlation could be demonstrated between the decrease in brain electrical potentials and the intracranial pressure applied at a time of maximal cardiovascular stimulation. Different pathological mechanisms have been put forward, one of these being identified as pial arteriolospasms. Acting together with other factors these spasms might be responsible for the rapid drop in electrical activity of the brain current potentials.
Authors:
K Meinen; B Kremer; H Hücker; W Geisler
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Brain research     Volume:  86     ISSN:  0006-8993     ISO Abbreviation:  Brain Res.     Publication Date:  1975 Mar 
Date Detail:
Created Date:  1975-06-02     Completed Date:  1975-06-02     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0045503     Medline TA:  Brain Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  439-47     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Pressure*
Electrocardiography*
Electroencephalography*
Female
Intracranial Pressure*
Iris / blood supply*
Microcirculation*
Pia Mater / blood supply*
Rats
Spasm
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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