Document Detail


Intracranial pressure and glaucoma.
MedLine Citation:
PMID:  20040876     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE OF REVIEW: Glaucoma remains a disease with an unclear basic pathophysiology. The optic nerve travels through two pressurized regions: the intraocular space and the intracranial space. Some authors have suggested that the relationship between intraocular pressure and intracranial pressure may play a fundamental role in the development of glaucoma. RECENT FINDINGS: Recent studies have shown that intracranial pressure is lower in patients with glaucoma and normal-tension glaucoma. Conversely, intracranial pressure appears to be elevated in patients with ocular hypertension. Early mathematical modeling studies have suggested that the counterbalance provided by intracranial pressure would be an important factor in the development of glaucoma. SUMMARY: The relationship between intraocular pressure and intracranial pressure may play an important role in the development of glaucoma.
Authors:
John P Berdahl; R Rand Allingham
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Current opinion in ophthalmology     Volume:  21     ISSN:  1531-7021     ISO Abbreviation:  Curr Opin Ophthalmol     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-09     Completed Date:  2010-03-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9011108     Medline TA:  Curr Opin Ophthalmol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  106-11     Citation Subset:  IM    
Affiliation:
Vance Thompson Vision, 1310 W 22nd Street, Sioux Falls, South Dakota, USA. johnberdahl@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Glaucoma, Open-Angle / physiopathology*
Humans
Intracranial Pressure / physiology*
Intraocular Pressure / physiology*
Ocular Hypertension / physiopathology
Grant Support
ID/Acronym/Agency:
EY07065/EY/NEI NIH HHS; EY15736/EY/NEI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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