Document Detail

Intracranial plasma cell granuloma: case report and treatment of recurrence with methotrexate and 6-mercaptopurine.
MedLine Citation:
PMID:  16282891     Owner:  NLM     Status:  MEDLINE    
Plasma cell granulomas are a rare form of idiopathic inflammatory pseudotumors often characterized by non-neoplastic proliferation of plasma cells, clinically mimicking a neoplastic process. Pseudotumors of the central nervous system, however, are exceptional and rare. The authors describe a 14-year-old girl with a mass lesion extending medially along the cavernous sinus into the right middle cranial fossa and pterygopalatine and infratemporal fossae. The authors review the current literature and discuss successful treatment with methotrexate and 6-mercaptopurine after recurrence of disease following radiation therapy and steroids.
Mona D Shah; Kenneth L McClain
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric hematology/oncology     Volume:  27     ISSN:  1077-4114     ISO Abbreviation:  J. Pediatr. Hematol. Oncol.     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-11-11     Completed Date:  2006-01-05     Revised Date:  2011-10-06    
Medline Journal Info:
Nlm Unique ID:  9505928     Medline TA:  J Pediatr Hematol Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  599-603     Citation Subset:  IM    
Texas Children's Cancer Center and Hematology Service, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030-2399, USA.
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MeSH Terms
6-Mercaptopurine / therapeutic use*
Brain Diseases / drug therapy*,  pathology
Drug Therapy, Combination
Granuloma, Plasma Cell / drug therapy*,  pathology
Magnetic Resonance Imaging
Methotrexate / therapeutic use*
Reg. No./Substance:
50-44-2/6-Mercaptopurine; 59-05-2/Methotrexate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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