Document Detail

Intracranial pressure/cerebral perfusion pressure-targeted management of life-threatening intracranial hypertension complicating diabetic ketoacidosis-associated cerebral edema: a case report.
MedLine Citation:
PMID:  22766587     Owner:  NLM     Status:  In-Data-Review    
ABSTRACT: Symptomatic cerebral edema from diabetic ketoacidosis occurs infrequently but carries a high rate of mortality and morbidity owing to complications from intracranial hypertension. Treatment options are limited but include hyperosmolar therapy with mannitol or hypertonic saline, tracheal intubation for airway protection, and hyperventilation via mechanical ventilation. We describe here the successful use of an intracranial pressure/cerebral perfusion pressure-targeted management strategy through ventriculostomy catheter placement with intracranial pressure monitoring and cerebrospinal fluid drainage, hyperosmolar therapy with hypertonic saline, and controlled hyperventilation to treat life-threatening complications of cerebral edema in a pediatric patient with severe diabetic ketoacidosis.
Sushant Srinivasan; Brian Benneyworth; Hugh J L Garton; Shawn L Hervey-Jumper; Patricia L Raimer; Folafoluwa O Odetola; Yong Y Han
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric emergency care     Volume:  28     ISSN:  1535-1815     ISO Abbreviation:  Pediatr Emerg Care     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-07-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8507560     Medline TA:  Pediatr Emerg Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  696-8     Citation Subset:  IM    
From the *Department of Pediatrics, School of Medicine and Public Health, University of Wisconsin Madison, WI; and †Department of Neurosurgery, University of Michigan Health System, Ann Arbor, MI.
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