Document Detail

Intracranial meningiomas and epilepsy: incidence, prognosis and influencing factors.
MedLine Citation:
PMID:  10604605     Owner:  NLM     Status:  MEDLINE    
In a retrospective study of a consecutive series of 222 surgically treated meningiomas, it was found that 26.6% of the patients presented epilepsy as their initial symptom. In this group, surgical excision of the intracranial meningiomas stopped the epilepsy in about 62.7% of the patients. But approximately one-fifth of the patients with intracranial meningiomas and no history of preoperative epilepsy developed new onset postoperative seizures. Of the patients with early onset of postoperative epilepsy, epilepsy appeared in 66.7% within first 48 h after surgery. Of the patients with postoperative epilepsy, 71.2% were seizure-free following 1 year of anticonvulsant therapy. Regarding preoperative existing factors, intracranial meningiomas located at supratentorium, convexity, and with evidence of or severe peritumoral edema significantly contributed to preoperative epilepsy. And in patients with preoperative epilepsy, those tumors with evidence of or severe perifocal edema and cerebral edema at the operative site were significantly more likely to suffer from postoperative epilepsy.
A S Lieu; S L Howng
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Epilepsy research     Volume:  38     ISSN:  0920-1211     ISO Abbreviation:  Epilepsy Res.     Publication Date:  2000 Jan 
Date Detail:
Created Date:  2000-01-24     Completed Date:  2000-01-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8703089     Medline TA:  Epilepsy Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  45-52     Citation Subset:  IM    
Department of Neurosurgery, Kaohsiung Medical College Hospital, Kaohsiung City, Taiwan, ROC.
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MeSH Terms
Brain Neoplasms / complications*,  epidemiology,  surgery
Epilepsy / epidemiology,  etiology*,  surgery
Functional Laterality / physiology
Meningioma / complications*,  epidemiology,  surgery
Middle Aged
Retrospective Studies

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