| Intracranial infantile hemangiomas associated with PHACE syndrome. | |
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MedLine Citation:
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PMID: 17213418 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND PURPOSE: Head and neck infantile hemangiomas are common lesions that are rarely observed in an intracranial location. We report 4 patients with orbital infantile hemangiomas and ipsilateral enhancing intracranial lesions, presumed to be infantile hemangiomas. METHODS: Imaging studies and medical records of 4 infants with orbital hemangiomas and enhancing intracranial lesions were reviewed. The intracranial lesions were evaluated in terms of their location, signal intensity characteristics, enhancement pattern, and degree of involution following treatment. Additional findings associated with PHACE syndrome were also noted and a literature review of intracranial infantile hemangiomas and PHACE syndrome was also performed. RESULTS: The intracranial masses were primarily in or adjacent to the internal auditory canal and demonstrated imaging characteristics and treatment response similar to the ipsilateral orbital lesions. Ipsilateral internal carotid artery hypoplasia, ipsilateral cerebellar hemisphere hypoplasia, and/or other head and neck hemangiomas were present in all patients. CONCLUSION: These cases collectively support the diagnosis of intracranial infantile hemangiomas and suggest a unique radiographic association between PHACE syndrome and intracranial infantile hemangiomas. |
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Authors:
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C D Judd; P R Chapman; B Koch; C J Shea |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: AJNR. American journal of neuroradiology Volume: 28 ISSN: 0195-6108 ISO Abbreviation: AJNR Am J Neuroradiol Publication Date: 2007 Jan |
Date Detail:
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Created Date: 2007-01-10 Completed Date: 2007-03-14 Revised Date: 2008-02-14 |
Medline Journal Info:
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Nlm Unique ID: 8003708 Medline TA: AJNR Am J Neuroradiol Country: United States |
Other Details:
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Languages: eng Pagination: 25-9 Citation Subset: IM |
Affiliation:
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Inland Imaging, Spokane, Washington 99202, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Brain Neoplasms / diagnosis*, drug therapy Carotid Artery, Internal / abnormalities* Cerebellopontine Angle / pathology Cerebellum / abnormalities, pathology Dominance, Cerebral / physiology Facial Neoplasms / diagnosis*, drug therapy Female Head and Neck Neoplasms / diagnosis*, drug therapy Hemangioma / diagnosis*, drug therapy Humans Infant Infant, Newborn Injections, Intralesional Magnetic Resonance Imaging* Male Orbital Neoplasms / diagnosis*, drug therapy Prednisolone / administration & dosage Prednisone / administration & dosage Syndrome Tomography, X-Ray Computed* Triamcinolone / administration & dosage |
| Chemical | |
Reg. No./Substance:
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124-94-7/Triamcinolone; 50-24-8/Prednisolone; 53-03-2/Prednisone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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