Document Detail


Intracranial hypertension in pediatric patients with acute lymphoblastic leukemia.
MedLine Citation:
PMID:  19058211     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Acute lymphoblastic leukemia (ALL) remains one of the most common malignancies of childhood. Between April 1999 and August 2004, 9 of 207 patients treated at a Tertiary Oncology Service for ALL presented with Intracranial Hypertension (IH). Seven of the patients met the diagnostic criteria for Idiopathic Intracranial Hypertension (IIH). Four of the patients were treated with cerebrospinal fluid (CSF) drainage alone and four required Acetazolamide. Two of the four patients who were treated with Acetazolamide required subsequently a lumbar-peritoneal (LP) shunt. One patient succumbed to his disease before receiving any specific treatment.
Authors:
George Vartzelis; Donna Lancaster; Penny Fallon
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric blood & cancer     Volume:  52     ISSN:  1545-5017     ISO Abbreviation:  Pediatr Blood Cancer     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2009-01-15     Completed Date:  2009-01-30     Revised Date:  2009-07-20    
Medline Journal Info:
Nlm Unique ID:  101186624     Medline TA:  Pediatr Blood Cancer     Country:  United States    
Other Details:
Languages:  eng     Pagination:  418-20     Citation Subset:  IM    
Affiliation:
Department of Pediatric Neurology, St George's Hospital, London, UK.
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MeSH Terms
Descriptor/Qualifier:
Acetazolamide / therapeutic use
Adolescent
Child
Child, Preschool
Female
Humans
Intracranial Hypertension / complications*,  drug therapy
Male
Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications*,  drug therapy
Chemical
Reg. No./Substance:
59-66-5/Acetazolamide
Comments/Corrections
Comment In:
Pediatr Blood Cancer. 2009 Sep;53(3):513; author reply 514   [PMID:  19418551 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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