Document Detail

Intracranial hemorrhage from an aneurysm encased in a pilocytic astrocytoma--case report and review of the literature.
MedLine Citation:
PMID:  11305772     Owner:  NLM     Status:  MEDLINE    
The authors present an unusual complication of a recurrent chiasmal/hypothalamic pilocytic astrocytoma. From his second year of life onwards, the patient was repeatedly operated on and also underwent external radiation therapy (54 Gy total dose) 1 month after the first subtotal tumor resection. Nine years after irradiation, the patient was referred to our center with a sudden onset of severe headache, vomiting and neck stiffness. Computed tomography, magnetic resonance imaging, and cerebral angiography demonstrated an intratumoral, intraventricular, and subarachnoidal hemorrhage from an anterior communicating artery aneurysm encased in the pilocytic astrocytoma. The aneurysm was clipped and the patient recovered nicely from the hemorrhage. Three years later, the patient suddenly died of cardiac failure. Autopsy disclosed vessel wall changes compatible with radiation-induced vasculopathy. In light of this finding, the importance of radiation therapy and intracranial neoplasms for aneurysm formation is discussed.
M Aichholzer; A Gruber; C Haberler; A Bertalanffy; I Slavc; T Czech
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery     Volume:  17     ISSN:  0256-7040     ISO Abbreviation:  Childs Nerv Syst     Publication Date:  2001 Feb 
Date Detail:
Created Date:  2001-04-17     Completed Date:  2001-07-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8503227     Medline TA:  Childs Nerv Syst     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  173-8     Citation Subset:  IM    
Department of Neurosurgery, University of Vienna, Medical School, Wien, Austria.
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MeSH Terms
Acute Disease
Astrocytoma / complications*,  pathology,  surgery
Cerebral Angiography
Child, Preschool
Fatal Outcome
Hypothalamic Neoplasms / complications*,  pathology,  surgery
Intracranial Aneurysm / complications,  etiology*,  pathology
Subarachnoid Hemorrhage / etiology*
Tomography, X-Ray Computed

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