Document Detail

Intracranial hemorrhage during extracorporeal membrane oxygenation in neonates.
MedLine Citation:
PMID:  3532015     Owner:  NLM     Status:  MEDLINE    
Intracranial hemorrhage is a complication of extracorporeal membrane oxygenation for the treatment of neonatal respiratory failure. A retrospective review of 35 neonates treated with extracorporeal membrane oxygenation was performed; ten had intracranial hemorrhage. Infants with intracranial hemorrhage had lower birth weights and were gestationally younger than infants with intracranial hemorrhage. Eight of eight neonates of less than 35 weeks' gestational age sustained intracranial hemorrhage. Six died immediately after extracorporeal membrane oxygenation was stopped. Two lived less than 1 year. Two of 27 neonates older than 34 weeks' gestational age sustained intracranial hemorrhage. One child is normal, the other died at 18 months of age. Based on the results of this study, the risk of intracranial hemorrhage appears low in neonates of greater than 34 weeks' gestational age who undergo extracorporeal membrane oxygenation treatment for severe respiratory failure. The use of extracorporeal membrane oxygenation, as it is presently performed, is contraindicated in neonates of less than 35 weeks' gestational age because of the risk of intracranial hemorrhage.
R E Cilley; J B Zwischenberger; A F Andrews; R A Bowerman; D W Roloff; R H Bartlett
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatrics     Volume:  78     ISSN:  0031-4005     ISO Abbreviation:  Pediatrics     Publication Date:  1986 Oct 
Date Detail:
Created Date:  1986-11-10     Completed Date:  1986-11-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376422     Medline TA:  Pediatrics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  699-704     Citation Subset:  AIM; IM    
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MeSH Terms
Cerebral Hemorrhage / etiology*
Extracorporeal Circulation
Gestational Age
Infant, Low Birth Weight
Infant, Newborn
Oxygenators, Membrane / adverse effects*
Respiratory Distress Syndrome, Newborn / therapy*
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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