Document Detail

Intracranial hemorrhage due to late hemorrhagic disease in two siblings.
MedLine Citation:
PMID:  16798155     Owner:  NLM     Status:  MEDLINE    
Deficiency of vitamin K predisposes to early, classic or late hemorrhagic disease of the newborn (HDN); late HDN may be associated with serious and life-threatening intracranial hemorrhage. Late HDN is characterized by intracranial bleeding in infants aged 1 week to 6 months due to severe vitamin K deficiency, occurring particularly in exclusively breastfed infants. Late HDN is still an important cause of mortality and morbidity in developing countries where vitamin K prophylaxis is not routinely practiced. In this study, we report on two siblings with intracranial bleeding who were fully breastfed without a routine supplementation of vitamin K. Vitamin K should be given to all newborns as a single, intramuscular dose of 1 mg.
Hüseyin Per; Sefer Kumandaş; Mehmet Akif Ozdemir; Hakan Gümüş; Musa Karakukcu
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of emergency medicine     Volume:  31     ISSN:  0736-4679     ISO Abbreviation:  J Emerg Med     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-06-26     Completed Date:  2006-10-20     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  8412174     Medline TA:  J Emerg Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  49-52     Citation Subset:  IM    
Department of Pediatric Neurology, Erciyes University Medical Faculty, Kayseri, Turkey.
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MeSH Terms
Diagnosis, Differential
Infant, Newborn
Intracranial Hemorrhages / diagnosis*,  etiology,  therapy
Tomography, X-Ray Computed
Vitamin K Deficiency / complications,  diagnosis*,  therapy
Vitamin K Deficiency Bleeding / diagnosis*,  etiology,  therapy

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