Document Detail

Intracranial hemorrhage as a complication of dobutamine stress echocardiography: case report and review of the literature.
MedLine Citation:
PMID:  22537238     Owner:  NLM     Status:  In-Data-Review    
Dobutamine stress echocardiography is a generally well-tolerated study to evaluate patients with suspected coronary artery disease. Rare but life-threatening complications of this study have been well described. Severe hypertensive responses are a known but uncommon adverse reaction to dobutamine infusion. The authors report a case of intracranial hemorrhage in the setting of severe hypertension as a complication of dobutamine stress echocardiography. The patient was on systemic anticoagulation with warfarin for a prosthetic mitral valve and had an international normalized ratio (INR) of 3.8 that was slightly over the therapeutic goal INR of 2.5-3.5. He had no predisposing intracranial lesions such as tumor, vascular malformation, or aneurysm. He suffered an intraparenchymal hemorrhage in three distinct areas of his brain. Intracranial hemorrhage related to dobutamine infusion has not been reported previously, but given the known risk of hypertension, life-threatening sequelae including intracranial hemorrhage are possible. (Echocardiography 2012;29:E119-E121).
Sachin P Shah; G Muqtada Chaudhry
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Echocardiography (Mount Kisco, N.Y.)     Volume:  29     ISSN:  1540-8175     ISO Abbreviation:  Echocardiography     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-04-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8511187     Medline TA:  Echocardiography     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E119-21     Citation Subset:  IM    
Copyright Information:
© 2011, Wiley Periodicals, Inc.
Lahey Clinic, Burlington, Massachusetts.
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