Document Detail


Intracranial haemorrhage in pre-viable, premature and full term foals.
MedLine Citation:
PMID:  6592094     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A neuropathological examination was carried out on the brains of 58 foals. Forty-two were pony foals induced at various periods of gestation from 200 days onwards. Two were pre-viable pony foals delivered by caesarean section and 14 were Thoroughbred foals (one set of twins, two stillborn, five premature, two dysmature, two convulsive and one induced). The only significant pathological change involved intracranial haemorrhage. Subarachnoid haemorrhage occurred in all of 10 pony foals induced before 301 days of gestation and in two pony foals born by caesarean section at 270 and 280 days gestation. Subarachnoid haemorrhage was also present in some pony and Thoroughbred foals born after 301 days gestation; the incidence usually appeared greater in those pony foals which survived for the shortest periods. Haemorrhage also occurred elsewhere in the brains, including the cerebral white matter, the molecular layer of the cerebellum and the medulla, but the intensity could not be related to either length of gestation or duration of survival. No other neuropathological changes were found that could account for the functional state of the animals, whether they were pre-viable, premature, dysmature or convulsive.
Authors:
A C Palmer; D P Leadon; P D Rossdale; L B Jeffcott
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Equine veterinary journal     Volume:  16     ISSN:  0425-1644     ISO Abbreviation:  Equine Vet. J.     Publication Date:  1984 Jul 
Date Detail:
Created Date:  1984-11-09     Completed Date:  1984-11-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0173320     Medline TA:  Equine Vet J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  383-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Animals, Newborn*
Brain / pathology*
Cerebral Hemorrhage / pathology,  veterinary*
Dinoprost
Female
Fetal Death / pathology,  veterinary
Horse Diseases / pathology*
Horses
Labor, Induced / veterinary
Luteolytic Agents
Pregnancy
Prostaglandins F
Prostaglandins F, Synthetic
Chemical
Reg. No./Substance:
0/Luteolytic Agents; 0/Prostaglandins F; 0/Prostaglandins F, Synthetic; 40666-16-8/fluprostenol; 551-11-1/Dinoprost

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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