Document Detail

Intracranial cerebral artery stenosis with associated coronary artery and extracranial carotid artery stenosis in Turkish patients.
MedLine Citation:
PMID:  18562145     Owner:  NLM     Status:  MEDLINE    
PURPOSE: Although it has been demonstrated that there is a high prevalence of extracranial carotid artery stenosis (ECAS) in patients with severe coronary artery disease, intracranial cerebral artery stenosis (ICAS) is rarely mentioned. We evaluated the prevalence of ICAS in patients with ECAS having elective coronary artery bypass grafting (CABG) surgery to determine the relations between ICAS, ECAS and atherosclerotic risk factors. METHODS: We retrospectively reviewed the digital subtraction angiography findings of 183 patients with ECAS> or =50% preparing for CABG surgery. The analyses focused on the intracranial or extracranial location and degree of the stenosis. The degree of extracranial stenoses were categorized as normal, <50%, 50-69%, 70-89%, and 90-99% stenosis and occluded. The degree of intracranial stenosis was classified as normal or < or =25%, 25-49%, and > or =50% stenosis and occluded. Traditional atherosclerotic risk factors were recorded. RESULTS: ECAS<70% in 42 patients and ECAS> or =70% in 141 patients. ICAS was found in 51 patients and ICAS> or =50% in 30 patients. Regarding risk factors, we found hypertension in 135 patients, diabetes mellitus in 91 patients, hyperlipidemia in 84 patients, and smoking in 81 patients. No risk factor was significant predictors of intracranial atherosclerosis. The severity of ICAS was not significantly associated with that of the ECAS. CONCLUSIONS: We found ICAS in 27.8% of the patients with ECAS>50% on digital subtraction angiography preparing for CABG. Therefore a complete evaluation of the neck vessels with magnetic resonance or catheter angiography seems to be indicated as well as intracranial circulation for the risk assessment of CABG.
Ozlem Alkan; Osman Kizilkilic; Tulin Yildirim; Hakan Atalay
Publication Detail:
Type:  Journal Article     Date:  2008-06-18
Journal Detail:
Title:  European journal of radiology     Volume:  71     ISSN:  1872-7727     ISO Abbreviation:  Eur J Radiol     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-09-14     Completed Date:  2009-12-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106411     Medline TA:  Eur J Radiol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  450-5     Citation Subset:  IM    
Department of Radiology, Baskent University, Faculty of Medicine, Ankara, Turkey.
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MeSH Terms
Aged, 80 and over
Angiography / statistics & numerical data*
Carotid Stenosis / diagnosis*,  epidemiology*
Intracranial Arteriosclerosis / diagnosis*,  epidemiology*
Middle Aged
Risk Assessment
Risk Factors
Turkey / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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