Document Detail

Intracranial aneurysms in sickle cell patients: report of 2 cases and review of the literature.
MedLine Citation:
PMID:  18614211     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The sickle cell disease has different neurologic complications, including cerebral aneurysms. This disease may lead to endothelial damage, which favors the development of cerebral aneurysms. Only a few cases demonstrated by cerebral angiography or surgery have been reported in the English literature referring to cerebral aneurysms in sickle cell patients. CASE DESCRIPTION: We report 2 patients with sickle cell disease whose cerebral aneurysms were successfully treated by open surgery. CONCLUSION: Sickle cell patients have a high occurrence of multiple aneurysms, and a high prevalence of posterior circulation aneurysms. This must be interpreted with caution, and further studies are needed to confirm this association.
Rafael Augusto Castro Santiago Brandão; Gervásio Teles C de Carvalho; Baltazar Leão Reis; Enderson Bahia; Atos Alves de Souza
Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2008-07-09
Journal Detail:
Title:  Surgical neurology     Volume:  72     ISSN:  1879-3339     ISO Abbreviation:  Surg Neurol     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-08-06     Completed Date:  2009-08-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0367070     Medline TA:  Surg Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  296-9; discussion 299     Citation Subset:  IM    
Department of Neurosurgery, Santa Casa Hospital, Faculty of Medical Science of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
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MeSH Terms
Anemia, Sickle Cell / complications*
Cerebral Angiography
Intracranial Aneurysm / complications*,  surgery*
Middle Aged
Subarachnoid Hemorrhage / etiology*,  surgery*
Tomography, X-Ray Computed
Treatment Outcome

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