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Intracranial Fusarium Fungal Abscess in an Immunocompetent Patient: Case Report and Review of the Literature.
MedLine Citation:
PMID:  25485222     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Introduction Fusarium spp is an omnipresent fungal species that may lead to fatal infections in immunocompromised populations. Spontaneous intracranial infection by Fusarium spp in immunocompetent individuals is exceedingly rare. Case Report An immunocompetent 33-year-old Hispanic woman presented with persistent headaches and was found to have a contrast-enhancing mass in the left petrous apex and prepontine cistern. She underwent a subsequent craniotomy for biopsy and partial resection that revealed a Fusarium abscess. She had a left transient partial oculomotor palsy following the operation that resolved over the next few weeks. She was treated with long-term intravenous antifungal therapy and remained at her neurologic baseline 18 months following the intervention. Discussion To our knowledge, this is the first reported case of Fusarium spp brain abscess in an immunocompetent patient. Treatment options include surgical intervention and various antifungal medications. Conclusion This case demonstrates the rare potential of intracranial Fusarium infection in the immunocompetent host, as well as its successful treatment with surgical aspiration and antifungal therapy.
Authors:
Asa Peterson; Martin H Pham; Brian Lee; Deborah Commins; Joseph Cadden; Steven L Giannotta; Gabriel Zada
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-11-12
Journal Detail:
Title:  Journal of neurological surgery reports     Volume:  75     ISSN:  2193-6358     ISO Abbreviation:  J Neurol Surg Rep     Publication Date:  2014 Dec 
Date Detail:
Created Date:  2014-12-8     Completed Date:  -     Revised Date:  2014-12-10    
Medline Journal Info:
Nlm Unique ID:  101601540     Medline TA:  J Neurol Surg Rep     Country:  -    
Other Details:
Languages:  ENG     Pagination:  e241-e245     Citation Subset:  -    
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