Document Detail

Intracortical EEG for the detection of vasospasm in patients with poor-grade subarachnoid hemorrhage.
MedLine Citation:
PMID:  20652443     Owner:  NLM     Status:  In-Process    
BACKGROUND: To study the feasibility of utilizing intracortical electroencephalography (ICE) including quantitative EEG (qEEG) analysis for the detection of vasospasm in five consecutive poor-grade SAH patients.
METHODS: Intracortical electroencephalography (ICE) was obtained via a single miniature parenchymal 8-contact depth electrode placed at the bedside. Quantitative EEG parameters, calculated on surface EEG and ICE, included alpha/delta ratio (ADR), mean amplitude, suppression percent, and total power. Percent changes between averaged values over 4-6 h of baseline EEG and EEG prior to angiography were calculated. The entire continuous qEEG recording for each patient was then reviewed to determine optimal automated alarm criteria.
RESULTS: ICE ADR was the most accurate for predicting angiographic vasospasm (5/5). ICE ADR decreased between baseline and follow-up by 42% (from 0.56 ± 0.07 to 0.32 ± 0.03) for those with vasospasm (N = 3) compared to 17% (0.62 ± 0.06 to 0.51 ± 0.03) for those without (N = 2). A sustained decrease in the ICE ADR from baseline (>25% for ≥ 4 h) occurred in all three patients with angiographically confirmed vasospasm and not in the two without; this decline occurred 1-3 days prior to angiographic confirmation.
CONCLUSIONS: Intracortical EEG is promising for detecting ischemia from vasospasm in poor-grade SAH patients, may be superior to scalp EEG, and allow automated detection, particularly using the ADR. Larger studies are needed to better define the effectiveness of this approach.
R Morgan Stuart; Allen Waziri; David Weintraub; Michael J Schmidt; Luis Fernandez; Raimund Helbok; Pedro Kurtz; Kiwon Lee; Neeraj Badjatia; Ron Emerson; Stephan A Mayer; E Sander Connolly; Lawrence J Hirsch; Jan Claassen
Related Documents :
12536053 - Alpha-[11c]-methyl-l-tryptophan pet identifies the epileptogenic tuber and correlates w...
20935323 - Eeg abnormalities in early and late onset alzheimer's disease: understanding heterogene...
3923773 - Aplastic anaemia: residue analysis of chlorinated hydrocarbons in human bone marrow bio...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurocritical care     Volume:  13     ISSN:  1556-0961     ISO Abbreviation:  Neurocrit Care     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101156086     Medline TA:  Neurocrit Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  355-8     Citation Subset:  IM    
Department of Neurological Surgery, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Investigation of Biosurfactant-Producing Indigenous Microorganisms that Enhance Residue Oil Recovery...
Next Document:  QTc interval and neurological outcomes in aneurysmal subarachnoid hemorrhage.