| Intracorporeal phenylephrine in the treatment of priapism. | |
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MedLine Citation:
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PMID: 7490814 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: The effectiveness and complications of intracorporeal phenylephrine without aspiration or irrigation as a treatment for priapism were assessed. MATERIALS AND METHODS: Nine consecutive patients who presented with priapism were treated with 0.5 mg. phenylephrine diluted in 2 cc normal saline injected directly into the corpus cavernosum. Blood pressure and pulse were measured before and after injection, and monitored every 15 minutes. If no detumescence was noted after 15 minutes the injection was repeated. Neither penile blood aspiration nor irrigation was performed. RESULTS: Of 9 patients 8 responded with detumescence. The number of injections required ranged from 1 to 6. No changes in blood pressure, heart rate or side effects were observed. CONCLUSIONS: We believe that this is a safe and effective method for treatment of priapism. Routine initial aspiration or irrigation of the corpora before intracorporeal injection of alpha-adrenergic agents does not appear to be necessary. |
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Authors:
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N Muruve; D H Hosking |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of urology Volume: 155 ISSN: 0022-5347 ISO Abbreviation: J. Urol. Publication Date: 1996 Jan |
Date Detail:
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Created Date: 1996-01-04 Completed Date: 1996-01-04 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376374 Medline TA: J Urol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 141-3 Citation Subset: AIM; IM |
Affiliation:
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Section of Urology, University of Manitoba, Winnipeg, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic alpha-Agonists
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administration & dosage* Adrenergic alpha-Antagonists / adverse effects Alprostadil / adverse effects Blood Pressure / drug effects Erectile Dysfunction / drug therapy Heart Rate / drug effects Humans Injections Male Papaverine / adverse effects Parasympatholytics / adverse effects Phentolamine / adverse effects Phenylephrine / administration & dosage* Priapism / chemically induced, drug therapy*, etiology Prospective Studies Time Factors Vasodilator Agents / adverse effects |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic alpha-Agonists; 0/Adrenergic alpha-Antagonists; 0/Parasympatholytics; 0/Vasodilator Agents; 50-60-2/Phentolamine; 58-74-2/Papaverine; 59-42-7/Phenylephrine; 745-65-3/Alprostadil |
| Comments/Corrections | |
Comment In:
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J Urol. 1996 Aug;156(2 Pt 1):483
[PMID:
8683713
]
J Urol. 1996 Jan;155(1):147 [PMID: 7490816 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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