Document Detail

Intracoronary injection of glycoprotein IIb/IIIa, abciximab, as adjuvant therapy in primary coronary intervention.
MedLine Citation:
PMID:  23394547     Owner:  NLM     Status:  Publisher    
Acute coronary syndromes and, in particular, ST - segment elevation myocardial infarction are the principle causes or mortality and morbidity in the industrialized countries. The manadgement of acute myocadial infarction is much debated in the literature; primary percutaneous coronary intervention is the treatment of choice. In the recent years there has been an increasing interest in the concept of adjunctive pharmacological therapy o improve outcomes in primary percutaneous coronary intervention. In the literature randomized trials of intravenous or more recently intracoronary injection of glycoprotein IIb/IIIa inhibitors have provided conflicting results with no definitive evidence for efficacy. The aim of the report is to review the evidence to our date on the role of intracoronary injection of abciximab during primary percutaneous intervention in the setting of acute myocardial infarction.
Andrea Rognoni; Alessadro Lupi; Chiara Cavallino; Roberta Rosso; Alessia Veia; Sara Sara Bacchini; Angelo Sante Bongo
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-2-04
Journal Detail:
Title:  Cardiovascular & hematological agents in medicinal chemistry     Volume:  -     ISSN:  1875-6182     ISO Abbreviation:  Cardiovasc Hematol Agents Med Chem     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-2-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101266881     Medline TA:  Cardiovasc Hematol Agents Med Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Coronary Care Unit and Catheterization Laboratory Hospital "Maggiore della Carità" Corso Mazzini 18, 28100 Novara, Italy. " Corso Mazzini 18, 28100 Novara, Italy.
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