Document Detail

Intracisternal tubules in a case of chronic lymphocytic leukaemia.
MedLine Citation:
PMID:  3039156     Owner:  NLM     Status:  MEDLINE    
In a case of chronic lymphocytic leukaemia we found that a few (less than 5%) of the circulating leukaemic lymphocytes contained inclusions of a type which do not appear to have been reported in the literature. The inclusions presented as solitary tubules or aggregates of parallel tubules lying within dilated cisternae of the rough endoplasmic reticulum and the perinuclear cistern. Some of the tubules were bounded by a single wall, others by a double wall. We also found a tubule bounded by three walls and another where a segment of the tubular profile was triple-walled and the remainder double-walled. We are inclined to think that the walls of these tubules are composed of membranes. The aetiogenic agent or agents responsible for the production of intracisternal tubules and their mode of formation are obscure.
M Kostianovsky; F N Ghadially
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of submicroscopic cytology     Volume:  19     ISSN:  0022-4782     ISO Abbreviation:  J. Submicrosc. Cytol.     Publication Date:  1987 Jul 
Date Detail:
Created Date:  1987-09-18     Completed Date:  1987-09-18     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0235232     Medline TA:  J Submicrosc Cytol     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  509-14     Citation Subset:  IM    
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MeSH Terms
Cell Nucleus / ultrastructure
Endoplasmic Reticulum / ultrastructure
Inclusion Bodies / ultrastructure*
Leukemia, Lymphoid / blood*
Microscopy, Electron
Middle Aged

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