Document Detail

Intracerebral haemorrhage and angiographic beading following ingestion of catecholaminergics.
MedLine Citation:
PMID:  4024187     Owner:  NLM     Status:  MEDLINE    
We report two cases of serious intracerebral haemorrhage occurring in young women following their first use of oral medications containing catecholaminergic agents (phenylpropanolamine in combination with ephedrine or pseudoephedrine). Both women were previously well, and there was no evidence for systemic vasculitis, coagulopathy, aneurysm or arteriovenous malformation. Angiography in both cases, performed approximately forty hours following drug ingestion, revealed the beading pattern typical of that seen in previously reported cases of presumed amphetamine-induced "vasculitis." We believe that this arteriographic abnormality is non-specific and should not be construed as necessarily indicative of arteritis.
A J Stoessl; G B Young; T E Feasby
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Stroke; a journal of cerebral circulation     Volume:  16     ISSN:  0039-2499     ISO Abbreviation:  Stroke     Publication Date:    1985 Jul-Aug
Date Detail:
Created Date:  1985-09-04     Completed Date:  1985-09-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0235266     Medline TA:  Stroke     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  734-6     Citation Subset:  IM    
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MeSH Terms
Cerebral Angiography
Cerebral Hemorrhage / chemically induced*
Ephedrine / adverse effects*
Hemianopsia / chemically induced
Hemiplegia / chemically induced
Phenylpropanolamine / adverse effects*
Reg. No./Substance:
14838-15-4/Phenylpropanolamine; 299-42-3/Ephedrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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