| Intracellular trafficking of perforin: to thwart a killer. | |
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MedLine Citation:
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PMID: 21703535 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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How do killer cells restrain perforin, the most potent toxin known to biologists, at its point of synthesis in the endoplasmic reticulum, where conditions are ideal for its activation? In this issue of Immunity, Brennan et al. (2011) study its trafficking, offering insights into protective mechanisms. |
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Authors:
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Christopher Froelich; Sunil Metkar |
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Publication Detail:
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Type: Comment; Journal Article |
Journal Detail:
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Title: Immunity Volume: 34 ISSN: 1097-4180 ISO Abbreviation: Immunity Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-06-27 Completed Date: 2011-08-22 Revised Date: 2011-09-26 |
Medline Journal Info:
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Nlm Unique ID: 9432918 Medline TA: Immunity Country: United States |
Other Details:
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Languages: eng Pagination: 823-5 Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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NorthShore University HealthSystems Research Institute, Evanston, IL 60201, USA. cfroelich@uchicago.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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| Grant Support | |
ID/Acronym/Agency:
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R01 AI044941-10/AI/NIAID NIH HHS |
| Comments/Corrections | |
Comment On:
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Immunity. 2011 Jun 24;34(6):879-92
[PMID:
21658975
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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