Document Detail


Intracellular pH signals in the induction of secondary pathways--the case of Eschscholzia californica.
MedLine Citation:
PMID:  16413947     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Transient peaks of the cytoplasmic pH are essential elements in a number of signal cascades that activate environmental responses or developmental processes in plant cells but little is known about the mechanisms of their generation. In many plant cells, elicitation of the hypersensitive response is preceded by a perturbation of the ionic balance at the plasma membrane including the inhibition of the proton pump and the influx of H+ from the apoplast. A basically different mechanism of cytoplasmic acidification that is fed by vacuolar protons has been discovered in cell suspensions of the California Poppy (Eschscholzia californica). These cells react to a yeast glycoprotein elicitor with the overproduction of benzophenanthridine alkaloids. Low elicitor concentrations trigger the biosynthesis of these phytoalexins without invoking elements of the hypersensitive response. Accumulated data support the existence of a signal path that includes the following steps: Links between the above events that connect them within a distinct signal path are substantiated by the phenotypes of transformed cell lines that either display lowered Galpha levels due to antisense transformation or express Galpha-binding antibodies in the cytoplasm. All of these cell lines lack the elicitor-activation of PLA2 and of vacuolar proton fluxes and show an impaired phytoalexin response to low elicitor concentrations. High elicitor concentrations trigger alkaloid biosynthesis via an increase of jasmonate at a pH-independent signal path.
Authors:
Werner Roos; Katrin Viehweger; Batsuch Dordschbal; Brigitte Schumann; Sven Evers; Jörg Steighardt; Wieland Schwartze
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Publication Detail:
Type:  Journal Article     Date:  2006-01-04
Journal Detail:
Title:  Journal of plant physiology     Volume:  163     ISSN:  0176-1617     ISO Abbreviation:  J. Plant Physiol.     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-01-23     Completed Date:  2006-03-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9882059     Medline TA:  J Plant Physiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  369-81     Citation Subset:  IM    
Affiliation:
Institute of Pharmaceutical Biology and Pharmacology, Department of Molecular Cell Biology, Martin-Luther-University Halle-Wittenberg, Kurt-Mothes-Str. 3, 06120 Halle (Saale), Germany. werner.roos@pharmazie.uni-halle.de
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MeSH Terms
Descriptor/Qualifier:
Alkaloids / biosynthesis
Cell Membrane / chemistry
Cytoplasm / chemistry
Eschscholzia / chemistry,  cytology,  metabolism*
Fungal Proteins / pharmacology
Gene Expression Regulation, Plant / drug effects
Hydrogen-Ion Concentration
Lysophosphatidylcholines / metabolism
Models, Biological
Phospholipases A / genetics,  metabolism
Phospholipases A2
Plant Extracts / biosynthesis
Plant Proteins / genetics,  metabolism
Proton-Translocating ATPases / metabolism
Signal Transduction*
Sodium-Hydrogen Antiporter / physiology
Terpenes
Vacuoles / chemistry,  metabolism
Chemical
Reg. No./Substance:
0/Alkaloids; 0/Fungal Proteins; 0/Lysophosphatidylcholines; 0/Plant Extracts; 0/Plant Proteins; 0/Sodium-Hydrogen Antiporter; 0/Terpenes; 37297-20-4/phytoalexins; EC 3.1.1.-/Phospholipases A; EC 3.1.1.4/Phospholipases A2; EC 3.6.3.14/Proton-Translocating ATPases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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