Document Detail


Intracellular hydrolysis of short chain glycerides by rat small intestine in vitro and transfer of glycerol.
MedLine Citation:
PMID:  5500736     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1. When triacetin, tripropionin and tributyrin are incubated with sacs of rat everted intestine, they enter the epithelial cells and are completely hydrolysed to free fatty acids and glycerol.2. The distribution between the mucosal and serosal fluids of the glycerol released is very different from that of the fatty acid. Although both hydrolytic products are accumulated in the serosal fluid, a much higher fraction of the fatty acid appears in this compartment.3. When glycerol is initially present in the mucosal fluid there is no evidence of its movement against a concentration gradient.4. The results confirm the existence of a transport mechanism for fatty acids released intracellularly but do not require the hypothesis of a special mechanism for glycerol transfer.
Authors:
J Howard; M J Jackson; D H Smyth
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of physiology     Volume:  208     ISSN:  0022-3751     ISO Abbreviation:  J. Physiol. (Lond.)     Publication Date:  1970 Jun 
Date Detail:
Created Date:  1971-04-03     Completed Date:  1971-04-03     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0266262     Medline TA:  J Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  461-71     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Biological Transport*
Comments/Corrections

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