Document Detail

Intracellular free iron and its potential role in ultrahigh-pressure-induced inactivation of Escherichia coli.
MedLine Citation:
PMID:  23124235     Owner:  NLM     Status:  MEDLINE    
Intracellular free iron of Escherichia coli was determined by whole-cell electron paramagnetic resonance spectrometry. Ultrahigh pressure (UHP) increased both intracellular free iron and cell lethality in a pressure-dose-dependent manner. The iron chelator 2,2'-dipyridyl protected cells against UHP treatments. A mutation that produced iron overload conditions sensitized E. coli to UHP treatment.
Yuan Yan; Joy G Waite-Cusic; Periannan Kuppusamy; Ahmed E Yousef
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Publication Detail:
Type:  Journal Article     Date:  2012-11-02
Journal Detail:
Title:  Applied and environmental microbiology     Volume:  79     ISSN:  1098-5336     ISO Abbreviation:  Appl. Environ. Microbiol.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2012-12-31     Completed Date:  2013-05-29     Revised Date:  2014-08-20    
Medline Journal Info:
Nlm Unique ID:  7605801     Medline TA:  Appl Environ Microbiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  722-4     Citation Subset:  IM    
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MeSH Terms
Electron Spin Resonance Spectroscopy
Escherichia coli / chemistry,  physiology*
Hydrostatic Pressure*
Iron / analysis,  toxicity*
Microbial Viability / drug effects*
Reg. No./Substance:
Erratum In:
Appl Environ Microbiol. 2013 Oct;79(20):6519

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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