| The Intracellular Metabolism of Legionella by Isotopologue Profiling. | |
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MedLine Citation:
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PMID: 23150394 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Metabolic pathways and fluxes can be analyzed under in vivo conditions by incorporation experiments using general (13)C-labeled precursors. On the basis of the isotopologue compositions in amino acids or other metabolites, the incorporation rates of the supplied precursors and the pathways of their utilization can be studied in considerable detail. In this chapter, the method of isotopologue profiling is illustrated with recent work on the metabolism of intracellular living Legionella pneumophila. |
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Authors:
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Klaus Heuner; Wolfgang Eisenreich |
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Publication Detail:
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Type: JOURNAL ARTICLE |
Journal Detail:
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Title: Methods in molecular biology (Clifton, N.J.) Volume: 954 ISSN: 1940-6029 ISO Abbreviation: Methods Mol. Biol. Publication Date: 2013 |
Date Detail:
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Created Date: 2012-11-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9214969 Medline TA: Methods Mol Biol Country: - |
Other Details:
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Languages: ENG Pagination: 163-181 Citation Subset: - |
Affiliation:
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Working group "Cellular Interactions of Bacterial Pathogens", Robert Koch-Institut, Berlin, Germany, heunerk@rki.de. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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