Document Detail

Intracardiac echocardiography: in vitro and in vivo validation for right ventricular volume and function.
MedLine Citation:
PMID:  8579028     Owner:  NLM     Status:  MEDLINE    
To determine the feasibility and accuracy of intracardiac ultrasonography (ICUS) for the measurement of right ventricular (RV) volumes and function, a 10 MHz ICUS catheter was used in an in vitro and in vivo model. In the in vitro study, 16 sheep hearts were imaged. Sequential cross-sectional images from RV apex to base were recorded during a calibrated pullback. Volumes were calculated by applying Simpson's algorithm. ICUS-obtained volumes correlated well with actual volumes (standard error of estimate [SEE] = 2.3 ml, r = 0.98). For the in vivo study, a beating-heart canine model was used (31 hemodynamic stages in six dogs). Actual volumes were measured by an intracavitary balloon connected to an external column. Sequential cross-sectional images were recorded during the ICUS catheter pullback from apex to base of the RV, and volumes calculated by Simpson's algorithm. Good correlations were observed between ICUS and actual values for diastolic (SEE = 4.1 ml, r = 0.97), systolic (SEE = 3.4 ml, r = 0.96), and ejection fraction (SEE = 3.1%, r = 0.87) values. This new technique can accurately quantitate RV volumes, can function both in vitro and in vivo, and has the potential for increasing applications to questions of clinical and research interest.
J A Vazquez de Prada; M H Chen; J L Guerrero; L R Padial; L Jiang; E Schwammenthal; A Sagie; A E Weyman; R A Levine; C Chen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American heart journal     Volume:  131     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1996 Feb 
Date Detail:
Created Date:  1996-03-11     Completed Date:  1996-03-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  320-8     Citation Subset:  AIM; IM    
Cardiac Ultrasound Laboratory, Massachusetts General Hospital, Boston, USA.
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MeSH Terms
Cardiac Volume
Echocardiography / methods*
Feasibility Studies
Heart Catheterization
Hypertrophy, Right Ventricular / ultrasonography*
Reproducibility of Results
Stroke Volume
Ultrasonography, Interventional / methods
Ventricular Function, Right*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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