Document Detail

Intraarterial injection of colforsin daropate hydrochloride for the treatment of vasospasm after aneurysmal subarachnoid hemorrhage: preliminary report of two cases.
MedLine Citation:
PMID:  16261335     Owner:  NLM     Status:  MEDLINE    
We describe two patients with symptomatic vasospasms after aneurysmal subarachnoid hemorrhage who were successfully treated with intraarterial injection of colforsin daropate hydrochloride (HCl). Colforsin daropate HCl is capable of directly stimulating adenylate cyclase, which in turn causes vasorelaxation via elevated intracellular concentrations of cyclic adenosine monophosphate. We suggest that colforsin daropate HCl might be a useful therapeutic tool in treating cerebral vasospasm.
S Suzuki; O Ito; T Sayama; S Yamaguchi; K Goto; T Sasaki
Related Documents :
10493365 - Comparison of transcranial doppler investigation of aneurysmal vasospasm with digital s...
20587225 - Arterial dissection and subarachnoid haemorrhage in human immunodeficiency virus-infect...
8252525 - A probably familial saccular aneurysm of the anterior communicating artery in a neonate.
8955435 - Does nimodipine influence sex difference in outcome after aneurysmal subarachnoid haemo...
2139485 - Hepatic artery infusion pumps: cannulation techniques and other surgical considerations.
17895165 - Carotid disease in acute stroke: a review.
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2005-10-28
Journal Detail:
Title:  Neuroradiology     Volume:  48     ISSN:  0028-3940     ISO Abbreviation:  Neuroradiology     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2006-01-11     Completed Date:  2006-09-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1302751     Medline TA:  Neuroradiology     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  50-3     Citation Subset:  IM    
Department of Neurological Surgery, Shin-Koga Hospital, Kurume, 830-8577, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Cerebral Angiography
Forskolin / administration & dosage,  analogs & derivatives*,  therapeutic use
Injections, Intra-Arterial
Middle Aged
Subarachnoid Hemorrhage / complications,  diagnosis,  drug therapy*
Tomography, Emission-Computed, Single-Photon
Vasospasm, Intracranial / diagnosis,  drug therapy*,  etiology
Reg. No./Substance:
0/colforsin daropate; 66428-89-5/Forskolin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Imaging features of copper deficiency myelopathy: a study of 25 cases.
Next Document:  An evaluation of immediate sheath removal and use of the Angio-Seal vascular closure device in neuro...