Document Detail

Intraaneurysmal flow changes affected by clip location and occlusion magnitude in a lateral aneurysm model.
MedLine Citation:
PMID:  12835071     Owner:  NLM     Status:  MEDLINE    
In order to study the flow dynamic changes inside an aneurysm sac due to the partial occlusion of the aneurysm neck, velocity fields were measured using a particle image velocitimeter (PIV) in in vitro aneurysm models under the physiological flow waveform. Lateral aneurysm models arising from the curved parent vessel with different occlusion ratios and sites-e.g. no clip, 50% proximal and distal clip, and 75% proximal and distal clip-were tested. Reduced inflow and intraaneurysmal velocities may provide a better hemodynamic environment for aneurysm embolization. Comparing inflow rates and averaged intraaneurysmal velocities in the proximal and the distal clip model, they were lower in the distal clip model in cases of 50% neck occlusion, but they were lower in the proximal clip model in cases of 75% occlusion. These results suggest that clipping sites for reduced inflow and intraaneurysmal flow velocities may differ for different residual neck sizes. Less effective inflow blocking in the 75% distally clipped model may be due to the curvature of the parent artery. Therefore, not only the residual neck size and clipping site but the geometry of parent vessel significantly affect the flow fields inside the aneurysm, and subsequently the success of the aneurysm treatment.
Hong Sik Byun; Kyehan Rhee
Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Medical engineering & physics     Volume:  25     ISSN:  1350-4533     ISO Abbreviation:  Med Eng Phys     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2003-07-01     Completed Date:  2004-04-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9422753     Medline TA:  Med Eng Phys     Country:  England    
Other Details:
Languages:  eng     Pagination:  581-9     Citation Subset:  IM    
Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
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MeSH Terms
Blood Flow Velocity*
Carotid Artery Diseases / physiopathology*,  surgery*
Carotid Artery, Internal / physiopathology,  surgery
Computer Simulation
Intracranial Aneurysm / physiopathology*,  surgery*
Models, Cardiovascular*
Surgery, Computer-Assisted / methods
Surgical Instruments*
Vascular Surgical Procedures / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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