| Intra-operative iodine-125 prostatic implant following bilateral pelvic lymphadenectomy. | |
| | |
MedLine Citation:
|
PMID: 6735755 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Sixty-five patients with prostatic adenocarcinoma Stages B and C were treated with intraoperative Iodine-125 prostatic implantation following bilateral pelvic lymphadenectomy. Pelvic nodal metastases were found in 31% of the patients: 23% (7/31) in clinical Stage B1 disease, 29% (8/28) in clinical Stage B2, and 83% (5/6) in clinical Stage C. All the patients have been followed for a period of 1 1/2 to 6 years. Serial digital rectal examination revealed complete regression of the palpable disease in 15% of the patients at 6 months, 47% at 1 year, and 87% at 2 years. Post-operative complications were also evaluated: 13% of the patients became sexually impotent, 11% had impaired potency after the procedure, and 16% of patients complained of dry ejaculation; and 17% developed scrotal and/or penile swelling, which persisted up to 14 months, but usually subsided within 5 months. Two patients developed local recurrence. Both patients responded to subsequent external radiation therapy of 7000 rad in 11 to 14 weeks with clinical regression of palpable disease. |
| | |
Authors:
|
E W Kwong; S H Huh; M P Nobler; H S Smith |
Related Documents
:
|
7540385 - Hytrin treatment of hypertension and benign prostatic hyperplasia. 11396235 - Oral estramustine therapy in serum chromogranin a-positive stage d3 prostate cancer pat... 15812205 - Local anesthesia reduces pain associated with transrectal prostatic biopsy. a prospecti... 16458775 - Decline in urinary retention incidence in 805 patients after prostate brachytherapy: th... 4084975 - Forty-five years of migraine--observations and reflections "from the inside" by a physi... 12565115 - Pilot study on the effect of tourniquet use on sufentanil pharmacokinetics. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: International journal of radiation oncology, biology, physics Volume: 10 ISSN: 0360-3016 ISO Abbreviation: Int. J. Radiat. Oncol. Biol. Phys. Publication Date: 1984 May |
Date Detail:
|
Created Date: 1984-08-01 Completed Date: 1984-08-01 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 7603616 Medline TA: Int J Radiat Oncol Biol Phys Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 665-70 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adenocarcinoma
/
radiotherapy*,
surgery Aged Brachytherapy* Combined Modality Therapy Humans Intraoperative Period Iodine Radioisotopes / administration & dosage* Lymph Node Excision* Lymphatic Metastasis Male Middle Aged Pelvis Prostatic Neoplasms / radiotherapy*, surgery |
| Chemical | |
Reg. No./Substance:
|
0/Iodine Radioisotopes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Investigation of changes in CT-number in the prostate after radiotherapy.
Next Document: Intestinal uptake of bile acids: effect of external abdominal irradiation.