| Intra-operative cooled-tip radiofrequency linear atrial ablation to treat permanent atrial fibrillation. | |
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MedLine Citation:
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PMID: 17956873 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: To demonstrate the safety and efficacy of saline irrigated cooled-tip atrial linear endocardial radiofrequency ablation (SICTRA) concomitant to open-heart surgical procedures in the treatment of permanent atrial fibrillation (AF). METHODS AND RESULTS: Two hundred and twenty-two patients presenting with permanent AF and the need for cardiac surgery were included. In addition to the cardio-surgical procedure [mitral valve (MV) surgery (n = 94), aortic valve replacement (n = 29), bypass surgery (n = 76 including 24 patients with additional MV surgery), and combined procedures (n = 23)] concomitant SICTRA was performed. In 116 patients, the ablation pattern was restricted to the left atrium alone. During the mean follow-up of 29 months, 174 patients (78%) converted to sinusrhythm (SR). In patients with SICTRA restricted to the left atrium conversion rates were not different compared to a biatrial approach (83 vs. 74%, P = 0.47). Thirty-days mortality was found to be 4% (9/222). Post-mortem evaluation revealed 23% of all lesions to be histologically non-transmural. In the overall group, only 4% of patients developed sustained secondary regular atrial arrhythmia. CONCLUSIONS: SICTRA safely and effectively restores stable SR in 78% of patients with permanent AF undergoing open-heart surgery. Rhythm outcome is not influenced by treatment of the right atrium. Sustained regular atrial arrhythmia with the need for invasive treatment strategies occurs in 4% although intra-operative ablation lesions are often non-transmural. |
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Authors:
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Thomas Deneke; Krishna Khargi; Bernd Lemke; Thomas Lawo; Michael Lindstaedt; Alfried Germing; Turgut Brodherr; Leif Bösche; Andreas Mügge; Axel Laczkovics; Peter H Grewe; Markus Fritz |
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Publication Detail:
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Type: Evaluation Studies; Journal Article Date: 2007-10-23 |
Journal Detail:
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Title: European heart journal Volume: 28 ISSN: 0195-668X ISO Abbreviation: Eur. Heart J. Publication Date: 2007 Dec |
Date Detail:
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Created Date: 2007-12-06 Completed Date: 2008-04-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8006263 Medline TA: Eur Heart J Country: England |
Other Details:
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Languages: eng Pagination: 2909-14 Citation Subset: IM |
Affiliation:
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University Heart Center Bochum, BG University-Hospital Bergmannsheil, Bürkle-de-la-Camp-Platz 1, 44789 Bochum, Germany. thomas.deneke@rub.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Aortic Valve / transplantation Atrial Fibrillation / mortality, surgery* Catheter Ablation / instrumentation*, methods Combined Modality Therapy / methods Coronary Artery Bypass / methods Follow-Up Studies Humans Intraoperative Period Middle Aged Mitral Valve / surgery |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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