Document Detail


Intra- and extracellular calcium in Ehrlich ascites tumor cell.
MedLine Citation:
PMID:  1180673     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Calcium concentration in intra- and extracellular fluid from Ehrlich ascites tumor cells has been studied. The higher content of calcium in the outer cell fluid appears as a possible factor determining the behavior of the cell membrane. While in the cytoplasm macromolecular compounds such as lipo- and nucleoproteins seem to play an important role in calcium-binding, in the extracellular fluid calcium is likely to be bound to small molecules (presumably short chain polyphosphates). The significance of calcium-binding changes at the cell membrane level in the carcinogenesis and in the physiological behavior of the tumor cells is discussed.
Authors:
L J Anghileri
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archiv für Geschwulstforschung     Volume:  45     ISSN:  0003-911X     ISO Abbreviation:  Arch. Geschwulstforsch.     Publication Date:  1975  
Date Detail:
Created Date:  1975-12-28     Completed Date:  1975-12-28     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0372411     Medline TA:  Arch Geschwulstforsch     Country:  GERMANY, EAST    
Other Details:
Languages:  eng     Pagination:  219-31     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Binding Sites
Calcium / analysis*
Calcium Radioisotopes
Carcinoma, Ehrlich Tumor / analysis*
Cell Membrane / analysis
Cytoplasm / analysis
Extracellular Space / analysis
Lipoproteins / analysis
Mice
Molecular Weight
Neoplasm Proteins / analysis
Nucleoproteins / analysis
Chemical
Reg. No./Substance:
0/Calcium Radioisotopes; 0/Lipoproteins; 0/Neoplasm Proteins; 0/Nucleoproteins; 7440-70-2/Calcium

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