| Intra-articular morphine and postoperative analgesia after knee arthroscopy. | |
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MedLine Citation:
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PMID: 12424044 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of this study was to evaluate the postoperative analgesic effect of intra-articular administration of a low- and a high-dose morphine solution after knee arthroscopy. Thirty patients who underwent diagnostic arthroscopy or arthroscopic meniscectomy were allocated in three groups. At the end of the arthroscopic procedure patients in Group A received intra-articularly 20 ml normal saline (N/S), Group B received 5 mg morphine in 20 ml N/S and Group C received 15 mg morphine in 20 ml N/S. The postoperative pain was assessed using a visual analogue scale for 24 h, while all the patients stayed at hospital. Side effects from the central action of opioids were not detected. Although the pain scores in the group of low-dose morphine were lower than in the control group, we failed to detect any significant differences in pain scores among the three groups. There was evidence that a high-dose can cause hyperalgesia. |
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Authors:
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G I Drosos; I G Vlachonikolis; A N Papoutsidakis; N S Gavalas; G Anthopoulos |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: The Knee Volume: 9 ISSN: 0968-0160 ISO Abbreviation: Knee Publication Date: 2002 Dec |
Date Detail:
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Created Date: 2002-11-08 Completed Date: 2003-03-12 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9430798 Medline TA: Knee Country: England |
Other Details:
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Languages: eng Pagination: 335-40 Citation Subset: IM |
Affiliation:
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Crete Naval Hospital, Souda, Crete, Greece. drosos@otenet.gr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Analgesics, Opioid / therapeutic use* Arthroscopy* Dose-Response Relationship, Drug Double-Blind Method Female Humans Injections, Intra-Articular Knee / surgery* Male Morphine / therapeutic use* Pain Measurement Pain, Postoperative / drug therapy* Prospective Studies Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Analgesics, Opioid; 57-27-2/Morphine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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