Document Detail

Intra-arterial tissue adhesive for medical splenectomy in humans.
MedLine Citation:
PMID:  7019959     Owner:  NLM     Status:  MEDLINE    
Bucrylate (isobutyl 2-cyanoacrylate) was used for the transcatheter embolization of the splenic artery in 4 patients with bleeding gastric varices secondary to splenic vein thrombosis, 3 patients with symptoms of hypersplenism, and 8 patients with bleeding esophageal varices secondary to portal hypertension. The splenic artery was completely occluded in 13 patients and partially occluded in 2. In all but one of the patients, functioning splenic tissue was preserved and no abscess developed. Medical splenectomy with Bucrylate appears to be a safe and effective method for treating bleeding gastric varices secondary to splenic vein thrombosis, and it can alleviate symptoms of hypersplenism. Its role in controlling bleeding from esophageal varices in patients with generalized portal hypertension is worth further study.
M L Goldman; P K Philip; M S Sarrafizadeh; I J Sarfeh; A A Salam; J T Galambos; S R Powers; J A Balint
Related Documents :
8938889 - Epistaxis in hereditary haemorrhagic telangiectasia.
16609349 - Rectus sheath hematoma: review of 126 cases at a single institution.
8421759 - Transjugular intrahepatic portosystemic shunts in patients with portal vein occlusion.
11244439 - Acute bleeding and thrombocytopenia after bone marrow transplantation.
839629 - Epidemiological evaluation of funduscopic findings in cerebrovascular diseases. iii. ob...
14618949 - A prospective comparative study of push and wireless-capsule enteroscopy in patients wi...
19411389 - Erythrocyte sedimentation rate, c-reactive protein, or rheumatoid factor are normal at ...
14569099 - Obesity is associated with worse peritoneal dialysis outcomes in the australia and new ...
6854399 - Clinical assessment of a radioimmunoassay for free thyroxine using a modified tracer.
Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Radiology     Volume:  140     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1981 Aug 
Date Detail:
Created Date:  1981-09-22     Completed Date:  1981-09-22     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  341-9     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Adhesives / therapeutic use*
Bucrylate / therapeutic use*
Child, Preschool
Clinical Trials as Topic
Cyanoacrylates / therapeutic use*
Embolization, Therapeutic / methods*
Esophageal and Gastric Varices / therapy
Hypersplenism / complications
Hypertension, Portal / complications
Middle Aged
Splenic Artery*
Stomach / blood supply
Thrombophlebitis / complications
Varicose Veins / etiology,  therapy*
Reg. No./Substance:
0/Adhesives; 0/Cyanoacrylates; 1069-55-2/Bucrylate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Aspergillosis and mucormycosis: two types of opportunistic fungal pneumonia.
Next Document:  Radionuclide studies of chronic schistosomal uropathy.