Document Detail


Intra-arterial revascularisation therapy for acute ischaemic stroke: initial experience in a Hong Kong hospital.
MedLine Citation:
PMID:  23535673     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
OBJECTIVES. To assess the outcome of acute ischaemic stroke patients who received intra-arterial therapy in our unit. DESIGN. Case series. SETTING. A tertiary hospital in Hong Kong. PATIENTS. Patients with ischaemic stroke due to large artery occlusion treated within 6 hours from symptom onset between January 2007 and May 2011. INTERVENTION. Acute intra-arterial revascularisation therapy. MAIN OUTCOME MEASURES. Primary outcome was functional independence (modified Rankin Scale score of ≤2) at 3 months. Secondary outcome was rate of recanalisation. Safety outcomes were symptomatic intracranial haemorrhage and 3-month mortality. RESULTS. Twenty-one patients with a mean age of 67 years fulfilled the inclusion criteria. Their mean National Institutes of Health Stroke Scale score was 18. The mean onset-to-puncture time was 212 minutes. Nine received intra-arterial tissue plasminogen activator alone, 11 had an adjunctive mechanical thrombectomy, and one received balloon angioplasty without tissue plasminogen activator. At the end of the procedure, thrombolysis grade 2a or better was attained in 18 (86%) of the patients, and 8 (38%) achieved functional independence at 3 months. Rates of symptomatic intracranial haemorrhage and 3-month mortality were 10% and 24%, respectively. CONCLUSION. In this setting, intra-arterial revascularisation therapy appeared safe and efficacious for this selected group of ischaemic stroke patients with large artery occlusions. Experience gained from this pilot study may help improve clinical outcomes of such patients.
Authors:
Edward Hc Wong; Simon Ch Yu; Alexander Yl Lau; Venus Sw Hui; Cecilia Sf Leung; Joyce Wy Hui; Deyond Yw Siu; Jill M Abrigo; K T Lee; Colin A Graham; Lawrence Ks Wong; Thomas Wh Leung
Related Documents :
23700173 - Fulminant viral myocarditis after rituximab therapy in pediatric nephrotic syndrome.
23784163 - Adherence and outcomes of patients treated with dabigatran: pharmacist-managed anticoag...
15286953 - Postoperative mortality following oesophagectomy and problems in reporting its rate.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine     Volume:  19     ISSN:  1024-2708     ISO Abbreviation:  Hong Kong Med J     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-03-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9512509     Medline TA:  Hong Kong Med J     Country:  China    
Other Details:
Languages:  eng     Pagination:  135-41     Citation Subset:  IM    
Affiliation:
Department of Medicine and Therapeutics, Prince of Wales Hospital, Shatin, Hong Kong.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Intracranial haemorrhage among Chinese children with immune thrombocytopenia in a Hong Kong regional...
Next Document:  Percutaneous nephrostomy, nephrolithotomy and combined ureteroscopic lithotripsy using the supine ap...