Document Detail

Intra-arterial Injection Fluorescein Videoangiography in Aneurysm Surgery.
MedLine Citation:
PMID:  23147788     Owner:  NLM     Status:  Publisher    
BACKGROUND:: To visualize blood flow in the arteries and aneurysm during surgery, intravenous fluorescence videoangiography has been used. However, the contrast of image by this procedure is diminished by repeated study, since the dye remains for about 10 minutes after injection. OBJECTIVE:: To determine the optimal dye concentration and clarify the usefulness of fluorescein videoangiography by intra-arterial dye injection. METHODS:: In the pilot study, fluorescein sodium dissolved at various concentrations was illuminated with excitation light, and fluorescence was detected by cameras. The fluorescence of 0.001% fluorescein sodium solution mixed with plasma at various concentrations was then examined. In 13 aneurysm patients, dye solution was administered through the catheter for intraoperative digital subtraction angiography. The intravenous injection method was also performed and the findings were compared. RESULTS:: Dye was clinically used at a concentration of 0.005 to 0.1% based on the results of the pilot study. Fluorescence emission from the vessels and aneurysms was clearly observed by both methods; however, arterial injection provided brighter emission, resulting in clearer demonstration of the blood stream than venous injection. Dye clearance was also quicker, which allowed repeat injections without delay. Dye filling in the aneurysm indicating incomplete occlusion was detected in two cases and occlusion of the perforating artery was observed in two cases. CONCLUSION:: Intra-arterial fluorescein videoangiography provides brighter and clearer imaging of blood flow with a smaller dose of dye than intravenous videoangiography. It can be repeated within a short time, and is useful to detect incomplete clipping or unexpected obstruction of arteries.
Katsuhiro Kuroda; Hiroyuki Kinouchi; Kazuya Kanemaru; Yoshihisa Nishiyama; Hideyuki Yoshioka; Toru Horikoshi
Related Documents :
10552358 - Aortic regurgitation reduces the accuracy of exercise echocardiography for diagnosis of...
21463548 - Comparison between arterial and venous sampling of circulating hormones, substrates and...
21205938 - Melody valve implantation into the branch pulmonary arteries for treatment of pulmonary...
11257078 - Human tissue valves in aortic position: determinants of reoperation and valve regurgita...
1561348 - Intracranial venous system in the newborn: evaluation of normal anatomy and flow charac...
8944998 - Improved bioresorbable microporous intravascular stents for gene therapy.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-26
Journal Detail:
Title:  Neurosurgery     Volume:  -     ISSN:  1524-4040     ISO Abbreviation:  Neurosurgery     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-11-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7802914     Medline TA:  Neurosurgery     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Neurosurgery, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi 1110 Shimokato, Chuo, Yamanashi 409-3898, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Basilar Tip Aneurysms: A Microsurgical and Endovascular Contemporary Series of 100 Patients.
Next Document:  Chronic lymphocytic leukemia: a tale of one or two signals?