Document Detail


Intra-aortic balloon pumping increases renal blood flow in patients with low left ventricular ejection fraction.
MedLine Citation:
PMID:  19181754     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Intra-aortic balloon pumping (IABP) has, for decades, been one of the key treatment modalities following impaired cardiac function after cardiac surgery. IABP increases cardiac output, decreases oxygen consumption of the heart and relieves the left ventricle. However, a number of complications have been reported in connection with IABP treatment. Only a few studies have evaluated renal blood flow and the purpose of this prospective study was to evaluate whether renal blood flow was affected by IABP treatment in high-risk patients. After approval from the county ethical committee and informed consent, seven consecutive patients with low left ventricular ejection fraction and scheduled for preoperative IABP treatment were allocated to the study. Assessment of renal blood flow was based on ultrasound spectral Doppler estimation of the flow velocity profiles in the interlobar kidney arteries. The result was described as balloon index (BI), which is maximal systolic velocity divided by the temporal mean velocity. Typical velocity profiles were demonstrated in all patients before, during and after IABP. BI measurement changed with time (p <0.05). BI was lower during IABP compared to both pre-IABP and post-IABP (p <0.025), indicating a higher renal blood flow. No statistically significant changes were seen in s-creatinine or creatinine clearance. Assuming unchanged diameter of kidney arteries and no considerable decrease in renal resistance and/or compliance, we conclude that the interlobar renal blood flow was significantly increased during IABP treatment, measured by ultrasound Doppler technique, but without a simultaneously significant change in creatinine clearance.
Authors:
E Sloth; P Sprogøe; C Lindskov; A Hørlyck; J Solvig; Cj Jakobsen
Related Documents :
4041344 - The effect of nisoldipine on apparent liver blood flow and effective renal plasma flow.
2877674 - Acute effects of bunazosin on aortic, vertebral, coronary and renal blood flows of anes...
17646464 - Ct quantification of effects of thalidomide in patients with metastatic renal cell carc...
626694 - Effect of pentazocine on renal blood flow.
20489034 - Onset of pulmonary ventilation in fetal sheep produces pial arteriolar constriction dep...
10517564 - Tissue distribution of mirtazapine (remeron) in postmortem cases.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Perfusion     Volume:  23     ISSN:  0267-6591     ISO Abbreviation:  Perfusion     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2009-02-02     Completed Date:  2009-05-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8700166     Medline TA:  Perfusion     Country:  England    
Other Details:
Languages:  eng     Pagination:  223-6     Citation Subset:  IM    
Affiliation:
Department of Anesthesia & Intensive Care Medicine, Aarhus University Hospital, Aarhus N, Denmark.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aged
Blood Flow Velocity
Cardiac Output
Creatinine / metabolism
Heart Failure / physiopathology*,  surgery*
Humans
Intra-Aortic Balloon Pumping*
Male
Metabolic Clearance Rate
Middle Aged
Oxygen Consumption
Preoperative Care
Prospective Studies
Renal Circulation / physiology*
Risk Factors
Ultrasonics
Ventricular Function, Left / physiology*
Chemical
Reg. No./Substance:
60-27-5/Creatinine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Interaction of plasma proteins with commercial protein repellent polyvinyl chloride (PVC): a word of...
Next Document:  Differences in displayed pump flow compared to measured flow under varying conditions during simulat...