Document Detail

Intra-abdominal spindle cell lesions: a review and practical aids to diagnosis.
MedLine Citation:
PMID:  11422475     Owner:  NLM     Status:  MEDLINE    
Intra-abdominal spindle cell lesions are uncommon and often present a diagnostic challenge. An important group of such lesions are the gastrointestinal stromal tumours. Other intra-abdominal spindle cell lesions include fibromatosis, various sarcomas-in particular, leiomyosarcoma, liposarcoma, and malignant peripheral nerve sheath tumour-and, in women, endometrial stromal sarcoma. Less common lesions are inflammatory myofibroblastic tumours, the mesenteric spindle cell reactive lesions, retroperitoneal fibrosis, and solitary fibrous tumour. A variety of intra-abdominal tumours of nonmesenchymal origin may have a spindle cell/sarcomatoid morphology; these include sarcomatoid carcinoma, malignant melanoma and, in women, sarcomatoid granulosa cell tumour. Finally, metastatic sarcomas from pelvic or extra-abdominal organs need also be considered. A set of practical aids to the diagnosis of intra-abdominal spindle cell lesions is presented to assist pathologists dealing with such lesions, particularly with regards to the consideration of differential diagnoses.
A Al-Nafussi; N A Wong
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Histopathology     Volume:  38     ISSN:  0309-0167     ISO Abbreviation:  Histopathology     Publication Date:  2001 May 
Date Detail:
Created Date:  2001-06-25     Completed Date:  2001-07-26     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7704136     Medline TA:  Histopathology     Country:  England    
Other Details:
Languages:  eng     Pagination:  387-402     Citation Subset:  IM    
Department of Pathology, University of Edinburgh Medical School, Teviot Place, Edinburgh EH8 9AG, UK.
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MeSH Terms
Abdominal Neoplasms / pathology*
Diagnosis, Differential
Fibroma / pathology
Gastrointestinal Neoplasms / pathology
Sarcoma / pathology

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