Document Detail


Intra-abdominal pressure monitoring in liver transplant recipients: a prospective study.
MedLine Citation:
PMID:  12528019     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: No data are available on the incidence and clinical relevance of increased intra-abdominal pressure after orthotopic liver transplantation. This study assessed abdominal hypertension in a population of transplanted patients as this may be an important cofactor in early postoperative complications. DESIGN AND SETTING: Prospective clinical study in an intensive care unit of a national health system teaching hospital PATIENTS AND MEASUREMENTS: Abdominal pressure was measured every 6 h using the urinary bladder method and was considered elevated when it was 25 mmHg or higher. Hemodynamic status was evaluated at the same times. Renal function was assessed on the basis of hourly urinary output by calculating serum creatinine on postoperative days 2 and 4 and the filtration gradient; patient outcomes were also considered. RESULTS: Intra-abdominal hypertension was observed in 32% of cases; the subjects with high abdominal pressure had significantly lower mean artery pressure values but did not differ in terms of central venous pressure or cardiac output. High intra-abdominal pressure was more frequently associated with renal failure, a lower filtration gradient, delayed postsurgical weaning from ventilation, and a worse outcome. CONCLUSIONS: Abdominal hypertension is frequent after liver transplantation and may be associated with a complicated post-operative course.
Authors:
Gianni Biancofiore; Maria L Bindi; Anna Maria Romanelli; Antonella Boldrini; Giovanni Consani; Massimo Bisà; Franco Filipponi; Antonio Vagelli; Franco Mosca
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Publication Detail:
Type:  Journal Article     Date:  2002-12-10
Journal Detail:
Title:  Intensive care medicine     Volume:  29     ISSN:  0342-4642     ISO Abbreviation:  Intensive Care Med     Publication Date:  2003 Jan 
Date Detail:
Created Date:  2003-01-15     Completed Date:  2003-06-05     Revised Date:  2005-03-07    
Medline Journal Info:
Nlm Unique ID:  7704851     Medline TA:  Intensive Care Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  30-6     Citation Subset:  IM    
Affiliation:
Department No 1 of Anesthesia and Intensive Care, Post-surgical and Transplant ICU, Azienda Ospedaliera Pisana, Ospedale di Cisanello, Via Paradisa 2, 56100 Pisa, Italy. g.biancofiore@med.unipi.it
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MeSH Terms
Descriptor/Qualifier:
Abdomen / physiopathology*
Female
Humans
Hypertension / diagnosis,  epidemiology*,  prevention & control
Italy / epidemiology
Kidney Failure, Acute / epidemiology,  etiology,  prevention & control
Liver Transplantation*
Logistic Models
Male
Middle Aged
Monitoring, Physiologic
Postoperative Complications / diagnosis,  epidemiology*,  prevention & control
Prospective Studies
ROC Curve
Risk Factors
Statistics, Nonparametric
Comments/Corrections
Comment In:
Intensive Care Med. 2004 Oct;30(10):1859   [PMID:  15378244 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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