Document Detail

Intra-abdominal leiomyosarcoma in a ferret (Mustela putorius Furo): histopathological and immunohistochemical characterization.
MedLine Citation:
PMID:  18525177     Owner:  NLM     Status:  MEDLINE    
A 5 years old female ferret with an abdominal palpable mass confirmed at echo-graphic examination died during an explorative laparotomy. A single lymph-node-like nodule was found adjacent to the intestinal loops. The round mass well circumscribed, solid and white, histologically, at low magnification, appeared encapsulated and built up by a population of atypical spindle cells arranged in interwoven fascicles. The cells had high anisocytosis degree, moderate mitotic activity and prominent nucleoli. A central area of necrosis was present. To characterise the tumour immunohistochemically cytokeratin, vimentin, S-100, melan-A, vWF, desmin, actin and alpha-actin were applied. Neoplastic cells resulted positive to vimentin, actin and alpha-actin. Based on the histological and immunohistological pattern a diagnosis of leiomyosarcoma was made.
Marzia Pezzolato; Katia Varello; Daniela Mascarino; Elisa Bozzato; Marta Vascellari; Elena Bozzetta
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of veterinary medical science / the Japanese Society of Veterinary Science     Volume:  70     ISSN:  0916-7250     ISO Abbreviation:  J. Vet. Med. Sci.     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-06-05     Completed Date:  2008-10-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9105360     Medline TA:  J Vet Med Sci     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  513-5     Citation Subset:  IM    
Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Area Neuroscienze e Genetica, Laboratorio di Immunoistopatologia, Torino, Italy.
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MeSH Terms
Abdominal Neoplasms / pathology,  veterinary*
Leiomyosarcoma / pathology,  veterinary*

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