Document Detail


Intra-abdominal "angiosarcomatosis" report of two cases after pelvic irradiation.
MedLine Citation:
PMID:  2013033     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Angiosarcomas account for only 1% to 2% of all soft tissue sarcomas with the most common site of origin being skin and subcutaneous tissue particularly on the face and scalp of elderly patients. These neoplasms rarely arise in the small or large bowel with presentation as diffuse abdominal "angiosarcomatosis." Two patients are reported who were treated with adjuvant pelvic irradiation for gynecologic malignancies (squamous cell carcinoma of the cervix and adenocarcinoma of the endometrium) in whom diffuse abdominal angiosarcoma of intestinal origin developed 7 and 18 years later. Both patients were treated with standard megavoltage irradiation. The clinical course was rapid in both cases with death due to intra-abdominal hemorrhage and bowel obstruction. The pertinent literature relating to the association between radiation therapy and subsequent development of angiosarcomas of soft tissues and other sites is briefly reviewed.
Authors:
R B Wolov; N Sato; N Azumi; E E Lack
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Cancer     Volume:  67     ISSN:  0008-543X     ISO Abbreviation:  Cancer     Publication Date:  1991 May 
Date Detail:
Created Date:  1991-05-15     Completed Date:  1991-05-15     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0374236     Medline TA:  Cancer     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2275-9     Citation Subset:  AIM; IM    
Affiliation:
Department of Pathology, Georgetown University School of Medicine, Washington, DC 20007.
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / radiotherapy
Aged
Aged, 80 and over
Carcinoma, Squamous Cell / radiotherapy
Female
Hemangiosarcoma / etiology*,  pathology
Humans
Intestinal Neoplasms / etiology*,  pathology
Neoplasms, Radiation-Induced / pathology*
Uterine Cervical Neoplasms / radiotherapy
Uterine Neoplasms / radiotherapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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