Document Detail


Intimal pulmonary artery sarcoma presenting as severe dyspnea and right heart insufficiency.
MedLine Citation:
PMID:  20523095     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Pulmonary artery sarcoma is a rare tumor with a poor prognosis. CASE REPORT: We report the case of a 64-year-old man with an intimal pulmonary artery sarcoma presenting with severe high oxygen flow-demanding dyspnea and weight loss of 12 kg in the last 6 months. On echocardiography, right heart insufficiency, markedly elevated right ventricular pressure, a pressure gradient along the right outflow tract, and a tumor mass adherent to the wall of the truncus pulmonalis were detected. The tentative diagnosis by echocardiographic findings was pulmonary artery sarcoma. Computed tomography of the thorax and 18-fluorodeoxyglucose positron emission tomography showed an advanced local tumor manifestation. Surgical resection of the tumor to improve hemodynamics confirmed the diagnosis. CONCLUSIONS: Pulmonary artery sarcoma should be considered as a rare differential diagnosis in patients with dyspnea due to right heart failure, particular in the case of additional weight loss, and echocardiographic examination is a useful first diagnostic approach in establishing the diagnosis.
Authors:
Michael Halank; Christiane Jakob; Martin Kolditz; Gerd Hoeffken; Utz Kappert; Gerhard Ehninger; Matthias Weise
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-05-11
Journal Detail:
Title:  Onkologie     Volume:  33     ISSN:  1423-0240     ISO Abbreviation:  Onkologie     Publication Date:  2010  
Date Detail:
Created Date:  2010-06-04     Completed Date:  2010-10-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7808556     Medline TA:  Onkologie     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  313-6     Citation Subset:  IM    
Affiliation:
Medizinische Klinik und Poliklinik I, Universitätsklinikum an der TU Dresden, TU Dresden, Germany. Michael.Halank@uniklinikum-dresden.de
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MeSH Terms
Descriptor/Qualifier:
Biopsy, Needle
Dyspnea / etiology*
Echocardiography, Doppler, Color
Echocardiography, Transesophageal
Fatal Outcome
Heart Failure / etiology*,  surgery
Humans
Lung / pathology
Lymphatic Metastasis / pathology
Male
Middle Aged
Neoplasm Invasiveness
Pneumonectomy
Pulmonary Artery / pathology*,  surgery
Sarcoma / pathology*,  surgery
Thoracoscopy
Tomography, X-Ray Computed
Tunica Intima / pathology*
Vascular Neoplasms / pathology*,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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